How Scientists Stored a Movie Inside DNA

If you thought flash drives were small, wait until you see this: Researchers have encoded the data to make a short video into the DNA molecules of bacteria. They also were able to retrieve the information from the genetic code and play back the movie.

To accomplish this feat, the first of its kind, the researchers started with five frames from a classic 1870s movie of a racehorse. Then, they broke these frames down into their pixels and used DNA to create a code for each pixel. The code contained information about the colour of the pixel and its location within the image.

Then, the researchers inserted short DNA fragments containing these codes into bacteria, and the bacteria incorporated the fragments into their genome. (Bacteria do this naturally.) Later, the scientists sequenced the bacterial DNA to reconstruct the movie with 90 percent accuracy.

Although it may seem like this project would have very limited applications to real life, researchers say they have goals far beyond the scope of the current study.

“The point is not to store videos in bacteria,” said study co-author Seth Shipman, a postdoctoral fellow at Harvard Medical School in Boston.

Instead, the researchers ultimately want to create “molecular recorders” capable of recording the events inside cells as they play out. This could give researchers insight into cellular events that are hard to observe in real-time, like the processes that occur during brain development.

“We want to turn cells into historians,” Shipman said in a statement. “We envision a biological memory system that’s much smaller and more versatile than today’s technologies, which will track many events non-intrusively over time.”

References:

Rachael Rettner (July 13, 2017). How Scientists Stored a Movie Inside DNA. LiveScience. Retrieved from https://buff.ly/3tTEwrS